Overview
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.2
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Read More
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Read More
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Read More
Most Useful Reviews
9
Reduced flushing
As I have considerable white hair, I tried active folic acid for the first time. After a week, I feel fine. I no longer experience the redness and hot flashes that came with niacin. The price is reasonable, though the packaging is somewhat basic. If it proves effective, I will purchase it again.
Read More
7.5
Enhanced energy
This quality product contains natural ingredients. Folic acid offers energy and alleviates hot flashes; it also positively influences metabolism and the nervous system.
Read More
7.5
Effective for hot flashes
4 people found this helpful
Effective and reasonably priced Folate. I use this product for hot flashes even though I've passed menopause. I believe my medications might be causing the hot flashes. It has proven very effective; when I ran out, they reappeared! The cost is reasonable, so I'm pleased. Additionally, I had read that one should take Folate, not folic acid.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.2
- All Researches
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Read More
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Read More
7
We explored whether folic acid supplementation could help alleviate hot flashes in postmenopausal women. The study highlighted that hot flashes often stem from changes in the body’s temperature control system, primarily due to decreased estrogen levels. This hormonal shift leads to increased activity of certain brain chemicals, specifically norepinephrine, and decreased levels of serotonin.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
Read More
4
We investigated the effects of folate in a study that included 51 postmenopausal women experiencing significant hot flashes. These women were carefully divided into groups: some received L-methionine, while others received a placebo, all while taking folate and methylcobalamin. The aim was to determine if folate could help alleviate the discomfort of hot flashes.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
Read More
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced flushing
As I have considerable white hair, I tried active folic acid for the first time. After a week, I feel fine. I no longer experience the redness and hot flashes that came with niacin. The price is reasonable, though the packaging is somewhat basic. If it proves effective, I will purchase it again.
Read More
7.5
Enhanced energy
This quality product contains natural ingredients. Folic acid offers energy and alleviates hot flashes; it also positively influences metabolism and the nervous system.
Read More
7.5
Effective for hot flashes
4 people found this helpful
Effective and reasonably priced Folate. I use this product for hot flashes even though I've passed menopause. I believe my medications might be causing the hot flashes. It has proven very effective; when I ran out, they reappeared! The cost is reasonable, so I'm pleased. Additionally, I had read that one should take Folate, not folic acid.
Read More
7.5
Improved symptoms
Things improved with the hot flashes, but my mother consumes a complex.
Read More
Frequently Asked Questions
9
Reduced flushing
As I have considerable white hair, I tried active folic acid for the first time. After a week, I feel fine. I no longer experience the redness and hot flashes that came with niacin. The price is reasonable, though the packaging is somewhat basic. If it proves effective, I will purchase it again.
7.5
Enhanced energy
This quality product contains natural ingredients. Folic acid offers energy and alleviates hot flashes; it also positively influences metabolism and the nervous system.
3
We conducted a double-blind, placebo-controlled trial involving 164 postmenopausal women suffering from frequent hot flashes. Over 12 weeks, half received a daily 5 mg folic acid supplement, while the other half received a placebo.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
Our findings revealed that folic acid did not significantly reduce the frequency or severity of hot flashes compared to the placebo. Some improvements were seen in quality of life measures after eight weeks, but overall, we couldn't confirm that folic acid effectively alleviates hot flashes.
9
We conducted a study with 70 menopausal women, randomly assigning them to receive either folic acid or a placebo for four weeks. Through questionnaires and hot flash diaries, we monitored changes in the severity, duration, and frequency of hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
Our findings revealed that folic acid treatment significantly reduced all three measures of hot flashes compared to the placebo, particularly in the later weeks of the treatment. This suggests that folic acid could be a valuable, low-risk option for managing menopausal hot flashes.
8
We investigated the effects of folic acid on hot flashes in postmenopausal women. In our study, 46 women were divided into two groups: one received daily folic acid supplements, while the other received a placebo for four weeks.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
Those taking folic acid reported a significant improvement in hot flashes compared to the placebo group. Additionally, we noted a reduction in a specific metabolite associated with norepinephrine in the women taking folic acid.
This suggests that folic acid may help alleviate hot flashes by affecting central nervous system activity.
7
We explored whether folic acid supplementation could help alleviate hot flashes in postmenopausal women. The study highlighted that hot flashes often stem from changes in the body’s temperature control system, primarily due to decreased estrogen levels. This hormonal shift leads to increased activity of certain brain chemicals, specifically norepinephrine, and decreased levels of serotonin.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
Our hypothesis was that folic acid might help ease these symptoms by interacting with the same brain chemicals that estrogen does. Over the years, research has shown that folic acid can produce an antidepressant-like effect, affecting both noradrenergic and serotonergic receptors in the brain. This raises the intriguing possibility that it could offer a similar benefit when it comes to managing hot flashes, although the specific effectiveness of folate on this issue is still under investigation.
While preliminary data supports our ideas, more research is needed to draw firm conclusions. It’s exciting to consider the potential of folic acid as a natural remedy for hot flashes, but we must proceed with caution until further evidence is available.
4
We investigated the effects of folate in a study that included 51 postmenopausal women experiencing significant hot flashes. These women were carefully divided into groups: some received L-methionine, while others received a placebo, all while taking folate and methylcobalamin. The aim was to determine if folate could help alleviate the discomfort of hot flashes.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
Despite the thoughtful setup and monitoring of participants, the results revealed no significant benefit of L-methionine for reducing hot flashes in comparison to the placebo group. We noted that both groups showed a decrease in hot flash frequency, but not enough to claim that folate had any positive effect.
It is important to highlight that folate was administered alongside L-methionine, making it challenging to isolate its potential impact on hot flashes. Consequently, while we explored its role, the findings suggest that folate alone might not play a significant part in managing this symptom for postmenopausal women.
References
- Ewies A, Ahmed I, Al-Azzawi F, Pitkin J, Gupta P, et al. Folic acid supplementation in postmenopausal women with hot flushes: phase III randomised double-blind placebo-controlled trial. BJOG. 2021;128:2024. doi:10.1111/1471-0528.16739
- Bani S, Hasanpour S, Farzad Rik L, Hasankhani H, Sharami SH. The effect of folic Acid on menopausal hot flashes: a randomized clinical trial. J Caring Sci. 2013;2:131. doi:10.5681/jcs.2013.016
- Gaweesh SS, Abdel-Gawad MM, Nagaty AM, Ewies AA. Folic acid supplementation may cure hot flushes in postmenopausal women: a prospective cohort study. Gynecol Endocrinol. 2010;26:658. doi:10.3109/09513591003686288
- Gaweesh S, Ewies AA. Folic acid supplementation cures hot flushes in postmenopausal women. Med Hypotheses. 2010;74:286. doi:10.1016/j.mehy.2009.09.010
- Guttuso T, McDermott MP, Ng P, Kieburtz K. Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial. Menopause. 2009;16:1004. doi:10.1097/gme.0b013e3181a2fa76
